Search on: ESTROGENIC STEROIDS, ALKYLATED 
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Descriptor English:   Estrogenic Steroids, Alkylated 
Descriptor Spanish:   Esteroides Estrogénicos Alquilados 
Descriptor Portuguese:   Esteróides Estrogênicos Alquilados 
Tree Number:   D06.472.334.851.437.968
Definition English:   Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties. 
Pharmacological Action:   Estrogens
 
History Note English:   2004 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   38106 
Unique Identifier:   D042782 

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